EVALUATION OF ANTIMICROBIAL AND ACUTE ANTI-INFLAMMATORY ACTIVITY OF SIDA CORDIFOLIA LINN SEED OIL

The oil obtained from Sida cordifolia seeds were found to possess anti microbial activity against E. coli, Staphylococcus aureus, Candida albicans and Aspergillus niger by using cup-plate method This property was comparable with standard drug norfloxacin and griseofulvin disc. Petroleum ether extract of Sida cordifolia seeds also possess anti-inflammatory activity against carrageenan induced paw edema in albino rats. The inflammation was reduced significantly at 180 minute and 0.375 (p< 0.01). A comparison with control group and standard drug diclofenac sodium, demonstrated that the values were significant. Key words: Sida cordifolia,, Anti microbial, Antifungal.

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